Nathália Evelyn Morais Costa

Organoselenium-containing monastrol analogs show preferential antileukemic activity and distinct cellular responses consistent with kinesin Eg5 engagement.

Selenium-containing dihydropyrimidinones (DHPMs) have emerged as promising scaffolds for anticancer drug development owing to their structural versatility and ability to modulate biologically relevant targets. Here, we investigated the antileukemic activity of two previously reported selenium-containing monastrol analo...