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Nathalie Große

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Open access Aug 2026

31 CD44-Gal9 Interaction between IDH1-mutant Grade 4 Astrocytoma and Microglia Promotes Invasion and Proliferation of Tumor Cells

IDH1-mutant grade 4 astrocytomas exhibit pronounced interactions with the tumor microenvironment that critically influence tumor progression. Tumor-associated microglia/macrophages (TAMs) are key mediators of these interactions, yet the molecular mechanisms governing tumor-TAM crosstalk remain incompletely unders...

Nathalie Große, F. Sahm, C. Herold-Mende et al. · 0 citations

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