MODULATION OF CARBOHYDRATE DIGESTION BY PLANT-DERIVED INHIBITORS OF MGAM AND SI SUBUNITS: A STRUCTURED NARRATIVE REVIEW APPLIED TO THREE BRAZILIAN CERRADO SPECIES
Postprandial hyperglycemia is a well-established therapeutic target in diabetes mellitus, and the intestinal α-glucosidases maltase-glucoamylase (MGAM) and sucrase-isomaltase (SI) catalyze the terminal step of starch digestion. As approved inhibitors have limited uptake due to gastrointestinal adverse effects, there re...