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Author

Neda Nikolovski

2 papers indexed here

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Open access Sep 2026

Minocycline ameliorates CNS autoimmunity through restraint of CD4+CD11bc+ cells

Minocycline is a tetracycline antibiotic with profound anti-inflammatory activity directed primarily against microglial cells and macrophages. Activation of nuclear factor erythroid 2-related factor 2 (Nrf2) is considered as an important target of minocycline. This drug has been considered a promising therapeutic for m...

Zorana Milosavljević, Milica Lazarević, Goran Stegnjaić et al. · 0 citations
Open access Sep 2026

FFAR2 activation induces IL-22-dependent intestinal immune responses to suppress CNS autoimmunity.

It is shown that selective oral activation of free fatty acid receptor 2 (FFAR2) with the synthetic agonist Cpd1 effectively ameliorates established experimental autoimmune encephalomyelitis (EAE), demonstrating therapeutic efficacy after the onset of the autoimmune response.

B. Jevtić, Milica Lazarević, Goran Stegnjaić et al. · 0 citations

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