Short-Chain Fatty Acids and FFAR2: Modulators of the Gut-Brain Axis in Neuroinflammatory Disorders.
Short-chain fatty acids (SCFAs), primarily acetate, propionate, and butyrate, are key microbial metabolites generated through the fermentation of indigestible carbohydrates by gut bacteria. Beyond their local actions in the intestinal environment, these metabolites exert far-reaching systemic effects, particularly in s...