Oct 2026
Spatially resolved genome architecture in mouse embryonic development.
Higher-order chromatin structure is linked to cell differentiation and aging, but its native distribution in tissues and role in organismal development remain unclear. Here, we introduce SpaceA, a spatial omics approach for in situ chromatin architecture profiling. Compared with high-throughput chromosome conformation...
Yuang Ma, Bo Gou, Yue-Tong Xu et al.
· Developmental Cell · 0 citations