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Author

Niannian Li

2 papers indexed here

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Review Open access Sep 2026

Dual role of ferroptosis in embryonic development, cascade amplification regulatory mechanism and targeted intervention

Ferroptosis is an iron-dependent regulated cell death driven by lipid peroxide accumulation. This review discusses its dual role in embryonic development. Physiologically, ferroptosis regulates cell fate and tissue remodeling through the synergistic GPX4-GSH and FSP1-CoQ10 pathways. Beyond passive cell death, iron-depe...

Fan Meng, Shi-Long Li, Xue-Ting Wang et al. · 0 citations
Review Open access Jul 2026

Metabolic reprogramming of cancer associated fibroblasts informs stromal heterogeneity and therapeutic targeting.

The tumor microenvironment (TME) refers to the non-malignant cellular and stromal components present within tumors, which play critical roles in cancer initiation, progression, metastasis, and therapeutic response. Among the diverse cellular constituents of the TME, cancer-associated fibroblasts (CAFs) represent a key...

Haicheng Ma, Hengxiao Lu, Zhenyu Zhang et al. · 1 citation

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