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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Nicholas C. Gervais

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Open access Aug 2026

CRISPR-activation reveals key resistance genes and vulnerabilities of copy number variants in Candida albicans

Additive fitness effects of individual gene overexpression are a significant predictor of the fitness of multiple isolates with CNVs and can explain fitness trade-offs observed between classes of antifungal drug for the CNV isolates.

Pétra L. Vande Zande, Nicholas C. Gervais, Erika Schell et al. · 0 citations
Open access Jul 2026

Chromosome-scale CRISPR screening reveals secretory pathway genes as drivers of aneuploidy-mediated antifungal tolerance

This work functionally dissects one of the most common aneuploidies observed in C. albicans, provides mechanistic insight into the molecular basis of antifungal tolerance, and establishes a generalizable framework for studying aneuploidy-mediated phenotypes across eukaryotic organisms.

Nicholas C. Gervais, Lauren F. Wensing, Manini Chhina et al. · 0 citations

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