Author

Nicholas G. Martin

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Open access Oct 2026

Association between polygenic liability to depression and lifetime depression in at-risk adolescents.

Internalising symptoms including depression, anxiety and somatic symptoms in adolescence are common. They can be transient, but they can also persist and progress to major depressive disorder (MDD) Polygenic risk scores for major depression (MD-PGS) may help identify which symptomatic adolescents are at greatest risk o...

E. Byrne, Nathan A. Gillespie, J. Najman et al. · Molecular Psychiatry · 0 citations

Open access Sep 2026

Robust inference and correlates from genetic associations with personality

Summary Paragraph Personality traits describe stable differences in how people think, feel, and behave and how they interact with and experience their social and physical environments1,2. Many questions remain unanswered about associations between DNA and personality traits, such as their robustness, generalizability,...

T. Schwaba, Margaret L. Clapp Sullivan, W. Akingbuwa et al. · Nature · 5 citations · ⚡1

Open access Jul 2026

Atypical energy-related symptoms define biologically distinct subtypes of major depressive disorder

Findings show that the directionality of neurovegetative symptoms indexes genetic heterogeneity within MDD, with metabolic biology as a central axis of differentiation.

A. Harder, Rujia Wang, Jacob Bergstedt et al. · medRxiv · 0 citations