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Author

Nicola Walker

2 papers indexed here

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Review Oct 2026

Non-enzymatic protein modifications at the interface of metabolism and immunity.

Immune cells are highly metabolically active throughout their life cycle, leading to elevated levels of a variety of reactive metabolites including reactive oxygen species, sugars, and lipid peroxidation products. These molecules covalently modify proteins, resulting in post-translational non-enzymatic covalent modific...

Nicola Walker, James J. Galligan, Y. David et al. · 0 citations
Open access Sep 2026

Linker Histone H1 Phosphorylation Promotes DNA Damage Repair during Replication Stress.

DNA replication fidelity depends on the integrity of the replication fork to prevent DNA damage and preserve genome stability. Disruptions to this process can trigger replication stress, leading to the accumulation of single-strand DNA (ssDNA) and double-strand breaks (DSBs), which drive mutagenesis and ultimately cont...

Brittney D. Bobowski, Sarah C. Faulkner, Hugo B Pinto et al. · 0 citations

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