Open access
Aug 2026
Cell-Based Sensor for Extracellular DNA
First-generation LUNAR constructs can detect both oligonucleotides and plasmid double-stranded DNA with nanomolar sensitivity in mammalian cells and future work will focus on improving sensitivity, fold-change, and multiplexing capabilities for sequence-specific DNA detection.
Boao Xia, Nicholas A. Kalogriopoulos, Ruoxin Wen et al.
· bioRxiv · 0 citations