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Author

Nidhi Sharma

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Review Open access Sep 2026

The P2X7R-NLRP3 inflammasome axis in Alzheimer’s disease and therapeutic potential of synthetic and plant-derived natural compounds: A review

This review summarizes the progressive molecular events linking Αβ and tau pathology to neuroinflammation via the P2X7R-NLRP3 inflammasome axis, while underscoring the therapeutic potential of plant-derived bioactive compounds as well as synthetic molecules in mitigating the progression of Alzheimer’s disease.

Rishabh Goswami, Nidhi Sharma, V. Jhawat et al. · 0 citations
Review Sep 2026

Beyond KRASG12C: emerging therapeutic strategies, patent landscape, and clinical progress in targeting KRAS-mutant cancers

The rapid evolution of KRAS-targeted therapeutic agents represents a shift from allele-specific inhibition towards a strategy that is mutation/context-dependent, thereby creating further clinical translation opportunities and increased patient benefit.

Srijita Chatterjee, S. Arya, Nidhi Sharma et al. · 0 citations

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