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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Nihan Bilge Satkin

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Aug 2026

Understanding the dynamic behavior of wild-type and mutant LARS1 proteins: insight from comparative molecular dynamics simulations.

Leucyl-tRNA synthetase 1 (LARS1) is a multi-domain enzyme essential for translational fidelity and amino acid sensing, with its anticodon-binding domain (ABD) playing a critical role in tRNA recognition. Missense variants in LARS1 have been associated with infantile liver failure syndrome type 1 (ILFS1), yet the struct...

Güzin Tunca Alparslan, Nihan Bilge Satkin, İbrahim Kamer et al. · 0 citations

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