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Author

Nikita A. Mitkin

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2 papers indexed here

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Review Open access Oct 2026

Irisin in Cardiovascular Health and Disease: A Review of Its Function as a Biomarker and Therapeutic Target in Atherosclerosis and Related Conditions

Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of mortality worldwide, necessitating novel biomarkers and therapeutic targets. Irisin, a myokine derived from FNDC5, has emerged as a molecule of interest owing to its pleiotropic effects, yet its role in cardiovascular health is debated amid con...

S. Dabravolski, S. Shityakov, Nikita A. Mitkin et al. · 0 citations
Open access Sep 2026

Semaglutide Attenuates Inflammatory Macrophage Polarization and Promotes Changes Associated with Mitochondrial Biogenesis Through cAMP-Dependent Signaling

Background/Objectives: Chronic metabolic inflammation is associated with pro-inflammatory macrophage activation and mitochondrial dysfunction. Semaglutide, a widely used GLP-1 receptor agonist, has been reported to possess systemic anti-inflammatory properties, but its action on human macrophages, especially in the con...

V. Pavshintsev, Aleksandra Zh Erbaeva, Alexey Vatlin et al. · 0 citations

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