High-resolution diffusion MRI of rectal cancer ex vivo surgical specimens reveals post-treatment microstructural characteristics of tissue components
Abstract Advances in organ-preserving rectal cancer treatment require accurate restaging after neoadjuvant therapy (NAT). However, standard tools - endoscopy and T 2 -weighted pelvic MRI - struggle to differentiate residual tumour from normal tissue and treatment-induced changes, yielding high specificity but low sensi...