Author

Nikolas A. Francis

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Open access Sep 2026

Mice detect and discriminate temporal patterns of mesoscale optogenetic cortical stimulation

Optogenetic stimulation is widely used to establish causal links between neural activity, behavior, and sensory perception, yet animals may also perceive the neural stimulation itself, a phenomenon termed “optoception.” We hypothesized that cortical optogenetic stimulation would generate an artificial percept that coul...

Gabrielle Stephens, Nikolas A. Francis · bioRxiv · 0 citations

Open access Sep 2026

Granger sensori-behavioral functional taxonomy of neuronal ensemble activity from two-photon calcium imaging data.

Understanding how neuronal populations interact to encode and transform sensory information is a fundamental challenge in computational neuroscience. Most existing studies, however, study neural encoding, behavioral readout, and functional connectivity as disjoint problems. Two-photon calcium imaging enables simultaneo...

Sahar Khosravi, Nikolas A. Francis, P. Kanold et al. · PLoS Computational Biology · 0 citations