Nilam Bhusare

Novel Acridone-Based EGFR Inhibitors: Design, Synthesis, and Integrated In Silico-In Vitro Evaluation.

The epidermal growth factor receptor (EGFR) family is a key biomarker and therapeutic target for cancer therapy. Although acridone scaffolds have previously inhibited other tyrosine kinases, their specific targeting of EGFR has not been reported. This study provides novel acridone-N-aceto/benzohydrazide derivatives wit...