Synthesis of imidazole derivatives and in silico/in vitro evaluation of potential antidiabetic activity
Diabetes mellitus (DM) is a chronic metabolic disorder characterized by persistent hyperglycemia due to insulin resistance or deficiency. The imidazole scaffold, a privileged heterocycle in medicinal chemistry, has shown significant promise in targeting key enzymes involved in type 2 DM (T2DM). In this study, eight nov...