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Nina C. Kathe

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Review Open access Sep 2026

Biomolecular condensates containing RNA: Nuclear magnetic resonance to the rescue.

Liquid-liquid phase separation (LLPS) drives the formation of membraneless organelles that are crucial for the spatial organization of eukaryotic cells. Given the critical role of biomolecular condensates in health and disease, it is important to gain a quantitative understanding of this phenomenon. Here, we summarize...

Johannes Schmoll, Nina C. Kathe, Mihajlo Novakovic et al. · 0 citations
Open access Jul 2026

Stabilizing Protein and Protein-RNA Condensates in Low-Melting Agarose Hydrogels for Quantitative Biophysical Measurements.

A detailed, step-by-step protocol for LMA stock preparation, droplet formation, and embedding is presented, and examples of specific downstream biophysical readouts are provided, showing that specific droplet properties are preserved after LMA embedding in the representative systems tested.

Nina C. Kathe, L. Emmanouilidis, Mihajlo Novakovic et al. · 1 citation

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