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Nina Cheng

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Open access Jul 2026

A systematic evaluation framework for universal antibody-antigen binding affinity prediction and candidate recommendation

This work proposes MochiBind, a sequence-only pairwise binding affinity predictor, and benchmark it against structure-derived baselines such as Boltz-2, GeoDock, and Graphinity, suggesting that sequence-based approaches can match or surpass structure-based models in generalization.

Yunrui Li, Yue Zhao, K. Sonmez et al. · 0 citations