Progressive multi-vertebral osteolysis, frequently misdiagnosed as malignancy or tuberculosis, can also be driven by a previously unrecognized infectious trigger. Here we demonstrate that sparganosis induces pronounced IgE-dependent osteoclastogenesis and severe bone destruction. Single-cell RNA analysis of periphera...
Yong-Ai Li, T. Meng, Ying-Qi Wang et al.· Cell Death & Disease· 0 citations
Emerging evidence for Vγ9Vδ2 T cell immunological memory provides a rationale for novel vaccine strategies, although the translatability of these findings to human TB remains to be established.
Zhi-Yun Shi, Yixin Ding, X. Jing et al.· Frontiers in Immunology· 0 citations
Histopathological comparison showed that STB and BS were both dominated by chronic inflammation but exhibited distinct lesion patterns, and Macro4 is best interpreted as a BS-associated lipid-remodelled macrophage state supported by convergent histological and transcriptomic evidence.
Qiang Liu, Han-Hua Guo, Jun-Xiao Liu et al.· Frontiers in Immunology· 0 citations
An uncertainty-guided deep learning segmentation framework improved spinal tuberculosis lesion segmentation accuracy and enhanced clinician trust, offering a robust AI decision-support tool for precise surgical planning.
Xing-Yu Duan, Jia-Xing Wang, Li-Nan Wang et al.· Frontiers in Physiology· 0 citations
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