Accurate preoperative discrimination between indolent and aggressive renal lesions is essential for personalized risk-stratified management and improves the clinical outcomes of renal tumor patients. This study aimed to establish and externally validate a non-invasive computed tomography (CT)-derived radiomic model for...
PURPOSE
Immediate urinary continence (UC) recovery following Retzius-sparing robot-assisted radical prostatectomy (RS-RARP) remains highly variable, highlighting the need for reliable preoperative prediction. We aimed to develop and validate models to identify patients likely to achieve immediate UC recovery following...
Bo-han Lin, Yang-Hua Chen, Zhi-Bin Ke et al.· International Brazilian Jour...· 1 citation
ABSTRACT Tripartite motif‐containing 59 (TRIM59) is an E3 ubiquitin ligase implicated in multiple malignancies, but its role in bladder cancer (BLCA) remains incompletely understood. In this study, we identified TRIM59 as a clinically relevant oncogenic driver in BLCA through integrated transcriptomic, clinical, and fu...
Junlin Gan, Xuesong Bai, Aijie Zhang et al.· Cancer Science· 0 citations
Ambient fine particulate matter (PM2.5) is an established environmental health hazard, but its role in clear cell renal cell carcinoma (ccRCC) progression remains incompletely understood. This study integrated epidemiological analysis, mechanistic experiments, transcriptomic profiling, and clinical tissue validation to...