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Open access Sep 2026

Spatiotemporal lineage tracing reveals the dynamic spatial architecture of tumor growth and metastasis

Tumor progression is driven by dynamic interactions between cancer cells and their surrounding microenvironment. Here we integrate high-resolution spatial transcriptomics and evolving lineage-tracing technologies to elucidate how tumor expansion, plasticity and metastasis co-evolve with microenvironmental remodeling in...

Matthew G. Jones, Da-Wei Sun, Kyung Hoi (Joseph) Min et al. · 0 citations
Open access Sep 2026

ResolVI: addressing noise and bias in spatial transcriptomics

Technologies for estimating RNA expression at high throughput, in intact tissue slices and with high spatial resolution (spatial transcriptomics) shed new light on how cells communicate and tissues function. A fundamental step in analyzing data generated by subcellular resolution spatial transcriptomics technologies is...

Can Ergen, Nir Yosef · 0 citations

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