Review
Open access
Sep 2026
Small-Molecule NANT Therapeutics Targeting the Brain–Immune Axis in Alzheimer’s Disease: Mechanisms, Clinical Progress, and Translational Challenges
This review provided a general review of small molecules for neuroinflammation-based NANT therapies in AD and found that they all suffered from late-stage treatment, patient heterogeneity, inadequate central nervous system penetration, and poorly designed preclinical studies.
Niti Sharma, Seong Soo A. An
· Molecules · 0 citations