Preprint
Jul 2026
Harmonised benchmarking of foundation models for single-cell and spatial transcriptomics reveals context-dependent generalisation
This benchmark provides practical guidance for model selection and argues that future models should be judged by biological generalisation, interpretability and perturbation-grounded validity, not by scale or leaderboard performance alone.
S. Chen, Roxana Zahedi, Lucy Chhuo et al.
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