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Jul 2026

Arid1b haploinsufficiency in excitatory neurons alters neocortical circuits but not social behavior or seizure phenotypes.

In mice with conditional Arid1b haploinsufficiency in excitatory neurons, an increase in the rate of synaptic connectivity between excitatory neurons and reduced strength of excitatory synapses to parvalbumin (PV)-expressing inhibitory interneurons is found.

Alec H. Marshall, Meretta A. Hanson, Danielle J. Boyle et al. · 0 citations