Jul 2026
Mechanoporation-based Intracellular Delivery of Functional Molecules for Primary Immune Cell Engineering 2252000
Efficient RNP-mediated knockout of surface MHC-I or TCRÉ’β in human T cells is demonstrated, and delivery of reporter mRNA and siRNA to monocytes and monocyte-derived dendritic cells for enabling transient gene expression and RNAi-mediated gene knockdown is demonstrated.
Ulrike Lambertz, Eric Ouellet, Quan Nguyen et al.
· Journal of Immunology · 0 citations