Author

Norifumi Iseda

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Open access Oct 2026

Prognostic Impact of the C-Reactive Protein-Albumin-Lymphocyte (CALLY) Index in Patients With Hepatocellular Carcinoma Undergoing Living Donor Liver Transplantation.

BACKGROUND The C-reactive protein-albumin-lymphocyte (CALLY) index reflects systemic inflammation, nutritional status, and immune competence. However, its prognostic significance in patients undergoing living donor liver transplantation (LDLT) for hepatocellular carcinoma (HCC) remains unclear. METHODS We retrospecti...

J. Mita, S. Itoh, T. Toshima et al. · Journal of hepato-biliary-pa... · 0 citations

Oct 2026

Prognostic Significance of PET− SUVmax in Patients Undergoing Resection of Hepatocellular Carcinoma >3 cm: A Retrospective Analysis

Background/Aim: Hepatocellular carcinoma (HCC) >3 cm often recurs after resection, indicating a need for better risk stratification. The 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) maximum standardized uptake value (SUVmax) reflects tumor aggressiveness. We evaluated the prognostic significance of pre...

T. Ishikawa, S. Itoh, Y. Kitamura et al. · Anticancer Research · 0 citations

Open access Aug 2026

Spatiotemporal dynamics of the tumor microenvironment in hepatocellular carcinoma during combination immunotherapy

The exploratory findings suggest that ATZ/BEV may remodel the HCC microenvironment toward a state characterized by concurrent CD8+ T-cell activation and inhibitory signaling through the TIGIT–PVR/NECTIN2 axis, particularly at the tumor margin.

Hitoshi Iwasaki, S. Itoh, K. Toshida et al. · Hepatology Communications · 0 citations