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Author

Nuntachai Surawatsatien

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Open access Oct 2026

A synthetic PGC1α co-activator reprograms microglial immunometabolism to preserve cone function in retinal degeneration

Retinitis pigmentosa (RP) is genetically heterogeneous, yet initiating mutations converge on primary rod degeneration followed by cone dysfunction and loss. Activated microglia are implicated in this secondary phase, but whether selective immunometabolic reprogramming of microglia preserves retinal function remains unk...

T. Winogrodzki, Jayvin Hernandez-Reyes, Rajvir Solanky et al. · 0 citations
Review Jul 2026

Retinal Pigment Epithelium and Microglia Transplantation in Age-related Macular Degeneration.

This review synthesizes current advancements in human embryonic and pluripotent stem cells platforms engineered for outer retinal reconstruction and addresses the microenvironmental challenges of transplanting allogeneic constructs into an inflamed, senescent host niche.

Nuntachai Surawatsatien, Rajvir Mukesh Solanky, Robert P. van de Werken et al. · 0 citations

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