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Author

O. Abdelkarem

2 papers indexed here

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Review Oct 2026

B-309 Codon 84 as a Potential Molecular Hotspot: Germline VHL p.Val84Met Presenting as Isolated Bilateral Pheochromocytoma

Von Hippel–Lindau disease (VHL) is an autosomal dominant cancer predisposition syndrome caused by pathogenic variants in the VHL gene, leading to impaired degradation of hypoxia-inducible factor (HIF) and dysregulated angiogenic signaling. Missense variants are commonly associated with pheochromocytoma-predominan...

O. Abdelkarem, M. Alam, M. Bhat et al. · 0 citations
Review Open access Sep 2026

Molecular Perspectives on Innate Immune Homeostasis: Interlocking Roles of Natural Killer and Dendritic Cells

An integrated framework for understanding how NK-DC interactions establish, maintain, and potentially restore immune homeostasis is proposed, in which Tregs act as downstream regulatory partners that reinforce peripheral tolerance rather than as equivalent components of the central NK-DC axis.

A. Hemdan, Nagla Usama, O. Abdelkarem · 0 citations

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