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O. Agbulut

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Open access Oct 2026

Ebselen restores mitochondrial function through metabolic rewiring in Barth syndrome and related mitochondrial diseases.

Despite major advances in the genetic diagnosis of mitochondrial disorders, effective disease-modifying therapies remain scarce. Here, we identify ebselen (EBS) as a promising therapeutic candidate through a phenotypic drug screen in a yeast model of Barth syndrome, a cardiomyopathy caused by defective cardiolipin matu...

Claire Almyre, Anne-Louise Cayer, Nolwenn Bounaix et al. · 0 citations
Open access Aug 2026

Generation and characterization of three human induced pluripotent stem cell lines from patients with Duchenne muscular dystrophy.

Three induced pluripotent stem cell lines reprogrammed from peripheral blood mononuclear cells (PBMCs) of patients with DMD constitute a relevant human cellular model for studying disease-associated phenotypes and evaluating potential therapeutic strategies.

Hamel Mahiou, Benjamin Marande, Lina El Kassar et al. · 0 citations

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