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O. Anakok

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Open access Sep 2026

Minimal CBX3-Derived UCOE Confers Long-Term Resistance to Transgene Silencing in Human iPSCs During Neuronal Differentiation

Long-term transgene silencing remains a major challenge in lentiviral gene delivery, particularly in pluripotent stem cells undergoing lineage-specific differentiation. Universal chromatin opening elements (UCOEs) have emerged as effective regulatory elements for protecting transgene expression against epigenetic silen...

O. Anakok, G. Akcay · 0 citations

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