Neurodevelopmental and psychiatric conditions have long been hypothesised to emerge from changes in the structure and function of the brain. However, the molecular and cellular mechanisms linking brain structure to these conditions remain unknown. Here, using genetic and structural/diffusion neuroimaging data from 59,2...
Y. He, A. Ebneabbasi, K. Rademaker et al.· medRxiv· 0 citations
It is demonstrated that the relationship between alcohol use and psychiatric disorders is driven by a complex, shared genetic architecture rather than environmental complications alone and underscores the value of multi-ancestry and cross-disorder genetic studies in SUD.
O. Andreassen, R. Icick, E. Wistrom et al.· International Journal of Neu...· 0 citations
Recent large-scale studies have enabled new knowledge about genetic underpinnings of morphological and electrophysiological alterations of the retina. Variation in retinal traits, often of neurodevelopmental origin, have been linked to major psychiatric disorders (MPDs). Here, we investigate the genetic overlap between...
P. Jahołkowski, N. Parker, I. Sveen et al.· medRxiv· 0 citations
It is found that schizophrenia and ADHD show distinct genetic patterns: schizophrenia shares more genetic factors with brain structure and diabetes, while ADHD is more strongly linked to metabolic pathways.
J. Kopal, A. Shadrin, D. van der Meer et al.· Communications Medicine· 0 citations
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