Abstract Background Major psychiatric disorders (MPDs) and premenstrual disorders (PMDs) are often comorbid, with indications of shared genetic architecture. However, the specific genetic variants underlying this comorbidity remain elusive. The aim of this study was to identify genomic loci shared between MPDs and PMDs...
P. Jahołkowski, E. Hysaj, N. Parker et al.· European psychiatry· 0 citations
By dissecting the genetic liability to SUD and SU and investigating their relationship with BIP, this work finds a genetic signature correlated with substance dependence but not substance use more broadly.
L. Ystaas, P. Parekh, N. Parker et al.· Biological Psychiatry· 0 citations
This work derived cortical brain organoids from a large cohort of schizophrenia (SCZ) patients and healthy controls and employed a comprehensive multiomics strategy to dissect the cellular mechanisms of long-term CLZ exposure, uncovered a SCZ-specific and metabolism-independent alternative splicing program that was ame...
I. Akkouh, Jordi Requena Osete, A. Szabo et al.· bioRxiv· 0 citations
Antisocial behaviour in youth has serious consequences at individual and societal level. Adolescence is also a critical period for the emergence of prodromal psychosis symptoms. Their co-occurrence may aggravate aggression and lead to severe adverse outcomes. Common genetic risk for psychosis, antisocial behaviour, and...
N. Tesli, P. Jahołkowski, J. Rokicki et al.· European Child and Adolescen...· 0 citations
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