Neurodevelopmental and psychiatric conditions have long been hypothesised to emerge from changes in the structure and function of the brain. However, the molecular and cellular mechanisms linking brain structure to these conditions remain unknown. Here, using genetic and structural/diffusion neuroimaging data from 59,2...
Y. He, A. Ebneabbasi, K. Rademaker et al.· medRxiv· 0 citations
Spatial transcriptomics maps gene expression at cellular resolution, revealing how cells organize into multicellular niches. Yet computational analyses remain dataset-specific, without a transferable representation of tissue organization that generalizes across datasets, tasks and tissues or predicts how tissues behave...
Sebastian Birk, M. V. Sanian, Amirhossein Vahidi et al.· bioRxiv· 4 citations· ⚡1
Language is a defining trait of our species, and disruptions in language acquisition can have profound consequences to the individuals affected. Uncovering the neurodevelopmental basis of this complex trait requires detailed molecular and cellular insights into the neocortical areas that support linguistic abilities. H...
Juan Moriano, Tanzila Mukhtar, J. Lee et al.· bioRxiv· 0 citations
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