The results define the dynamic architecture of the Rixosome and provide a structural framework for ITS2 processing during nuclear maturation of the eukaryotic 60S ribosomal subunit.
M. Thoms, Jing-Yi Zhu, Xia-Ying Hong et al.· bioRxiv· 0 citations
The yeast DHX29 homolog, Ylr419w (Dhx29), has a similar function during translation on elongating 80S ribosomes, and is proposed to functions in translation elongation by resolving structured mRNA formed in the ribosomal A-site through its 3’-5’ helicase activity and pulling on the mRNA from its 3’ end.
L. Chitoiu, T. Denk, Martin B. D. Müller et al.· bioRxiv· 0 citations
The opportunistic pathogen Pseudomonas aeruginosa ensures its survival by forming mechanically and chemically resistant biofilms, with cationic exopolysaccharide Pel as an abundant constituent of the structural matrix. Despite its biomedical relevance, the mechanisms of Pel synthesis and secretion via the trans-envelop...
Cristian Rosales-Hernandez, Marius Benedens, Julien Reißmann et al.· bioRxiv· 0 citations
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