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Ö. Çevik

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Open access Aug 2026

Organotin-Catalyzed Synthesis, Characterization, Anticancer and Antioxidant Activities, and Molecular Modeling Studies of Nimesulide Ureas as Potential MetAP (Type II) Inhibitors

In this study, a new series of nimesulide-derived ureas (3a–j) was designed and synthesized to investigate structural modifications of nimesulide and to evaluate their biological activity. The compounds were obtained in high yields (68–88%) under organotin-catalyzed conditions, and their structures were unequivocally e...

Yağmur Biliz, Özgür Yılmaz, Elif Kuloğlu et al. · 0 citations

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