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O. Chiba-Falek

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Open access Aug 2026

SNCA-targeted transcriptional repression therapy alleviates pathological and behavioral perturbations in a Parkinson's disease mouse model

In vivo proof-of-concept for SNCA-targeted transcriptional repression therapy in a PD-mouse model is provided and its further preclinical development toward investigational new drug enablement is supported.

Bernadette O'Donovan, Joseph E. Rittiner, Suraj Upadhya et al. · Neurotherapeutics · 0 citations