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Open access Aug 2026

Real-world effectiveness of trastuzumab deruxtecan in heavily pretreated her2-positive metastatic breast cancer: A single-center experience

Aim: Trastuzumab deruxtecan (T-DXd) has shown substantial activity in trials of HER2-positive metastatic breast cancer (mBC), but real-world data in heavily pretreated patients, in those with CNS metastases, and in patients started at reduced doses remain limited. To evaluate real-world efficacy and safety of T-DXd in...

Orçun Can, O. Demir · 0 citations

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