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Author

Ö. Demirel

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Open access 2026

Inflammatory Biomarkers in Bipolar and Unipolar Depression: Associations and Diagnostic Performance in a Tertiary Inpatient Setting

Objective: Increasing evidence suggests that inflammatory processes may play a role in the pathophysiology of mood disorders. However, the diagnostic utility of inflammatory biomarkers in distinguishing bipolar from unipolar depression remains unclear. Methods: This retrospective study included 810 inpatients diagnos...

M. Kırpınar, İ. Yıldırım, Sarp Yoldaş et al. · 0 citations
Open access Sep 2026

COMPARISON OF INFLAMMATORY AND METABOLIC PARAMETERS IN UNIPOLAR AND BIPOLAR DEPRESSION

Objective: Differentiating bipolar depression (BPD) from unipolar depression (UPD) remains a clinical challenge. This study aimed to compare inflammatory and metabolic parameters among hospitalized patients with UPD, BPD, and bipolar mania (BPM), and to evaluate potential biological differences between UPD and BPD.Mate...

M. Kırpınar, İ. Yıldırım, Sarp Yoldaş et al. · 0 citations
Open access Jul 2026

Common schizophrenia heritability concentrates in an evolutionarily young, brain-regulatory subset of fine-mapped credible-set variants

The persistence at common frequency of PGC3 schizophrenia common-variant heritability is most consistent with purifying selection and mutation-selection balance on these ancient, predominantly non-coding, brain-regulatory variants rather than recent adaptation.

Yusuf Çiçek, A. Altunç, H. A. Velioğlu et al. · 0 citations

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