Author

O. Distler

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Open access Aug 2026

The dual PPAR-α/δ agonist elafibranor attenuates TGF-β1-induced cardiac fibrosis through redox-metabolic and bioenergetic reprogramming in human cardiac models

M. Paw, L. Minder, A. Laimbacher et al. · bioRxiv · 0 citations

Open access Aug 2026

Lanifibranor (IVA-337) - a pan-PPAR agonist suppresses TGF-β1-induced cardiac fibrosis and rescues cardiomyocyte function

Lanifibranor attenuates TGF-β1-driven cardiac fibrosis by combining antifibrotic effects with metabolic and functional improvements in human models.

M. Paw, L. Minder, A. Laimbacher et al. · bioRxiv · 0 citations

Review Open access Aug 2026

The Role of Inflammation in the Pathogenesis of Pulmonary Fibrosis: Mechanisms and Treatment Implications.

Fibrotic interstitial lung diseases (fILDs) encompass a heterogeneous group of interstitial lung diseases (ILDs) and may arise from persistent inflammation caused by systemic disease or environmental exposures. Idiopathic pulmonary fibrosis (IPF), the prototypical fILD, is characterized by progressive fibrosis, limited...

Nazanin Nazemi, Bruno Crestani, D. Helou et al. · European Respiratory Journal · 0 citations