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Author

O. E. El Naggar

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Open access Jul 2026

PSGL-1 blockade delays relapse to BRAF/MEK inhibition in cutaneous melanoma

It is demonstrated that dual inhibition of BRAF/MEK and PSGL-1 elicits durable tumor control in a preclinical model of PD-1-refractory cutaneous melanoma, and antibody-mediated blockade of PSGL-1, in combination with BRAF/MEK inhibition, yields superior anti-tumor activity compared with either monotherapy.

O. E. El Naggar, Bn. Ha, ML Rakoto et al. · 0 citations

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