O. Elemento

NMR metabolomics for cardiovascular-kidney-metabolic risk stratification in an integrated healthcare system

Role of orphan G protein-coupled receptor GPR52 in breast cancer cell multicellular organization and collective invasion.

Loss of the orphan GPCR GPR52 in human breast cell lines leads to increased cell clustering, hybrid/partial EMT, and increased tumour burden in zebrafish, further expanding the understanding of mechanisms driving cancer progression and opening the door to novel therapeutic approaches.

Applying Artificial Intelligence and machine learning in precision nutrition

This Perspective synthesizes current AI/ML methodologies in PN, elucidates their interplay with the distinctive features of multi-omic and nutritional data, such as being compositional, episodic, context-dependent, and error-prone, and delineates nutrition-specific best practices for achieving robust, interpretable, an...

Constrained Generative Design Frameworks For Computational Discovery of Target-Specific DARPin Candidates

This work established a robust framework for identifying and prioritizing high-confidence DARPin candidates for experimental validation, and identified mesothelin-targeting DARPin candidates with predicted structural confidences approaching those of a structurally validated picomolar-affinity binder.