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Author

O. Mărginean

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Review Open access Sep 2026

Obesity, Oxidative Stress, and Inflammation in Precocious Puberty: Do All Roads Lead to the Hypothalamus?

Childhood obesity is consistently associated with earlier pubertal timing, particularly in girls, whereas its relationship with true central precocious puberty (CPP), defined by premature activation of the hypothalamic–pituitary–gonadal (HPG) axis, is less clearly established. An increased frequency of CPP diagnoses an...

T. Bizerea-Moga, F. Chisavu, L. Chișavu et al. · 0 citations
Case report Open access Aug 2026

Early-Onset TRNT1-Related SIFD Syndrome with an Additional Monoallelic C7 Variant: A Pediatric Case Report

This case highlights the importance of early genetic evaluation in infants with recurrent fever, microcytic anemia, immune abnormalities, and multisystem involvement and emphasizes the need for cautious interpretation of additional monoallelic pathogenic variants detected by broad genetic panels when functional confirm...

I. Jugănaru, Adriana Cojocaru, Andreea Grigoriță et al. · 0 citations

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