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Review Open access Aug 2026

Next-generation macrophage engineering in cancer therapy: From TAM reprogramming to CAR-macrophages

This review synthesizes current strategies across DNA, mRNA, and siRNA-based platforms, highlighting convergent design principles that connect TAM reprogramming with CAR-M development and discusses reshaping phagocytosis checkpoints, metabolic and transcriptional stabilization, cytokine augmentation, and synthetic rece...

O. Nilova, A. Zajakina · 0 citations

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