BACKGROUND
Polygenic scores (PGS) have been used to quantify genetic liability for psychiatric disorders, but it remains unclear how these scores are associated with age- and gender-specific risk of diagnosis.
AIMS
To examine associations between disorder-specific PGS and age- and gender-specific risk of psychiatric...
Genona T. Maseras, Dan-Ni Chen, C. Albiñana et al.· The British journal of psych...· 0 citations
It is found that from 2012 to 2022, children and adolescents diagnosed with ADHD or ASD became increasingly similar to peers without these diagnoses, suggesting that increasing diagnostic rates may reflect changes in diagnostic practices or health care capacity rather than changes in underlying risk alone.
Magnus Elias Tarp, M. L. Lousdal, C. U. Rask et al.· JAMA psychiatry· 1 citation
Background: Polygenic scores (PGSs) are increasingly used to investigate the genetic architecture of complex traits. In genetics, family study designs are often used to adjust for confounders such as population structure and shared environment. However, family studies may also be particularly vulnerable to to non-rando...
T. Gholipourshahraki, Ciarrah Barry, O. Plana-Ripoll et al.· medRxiv· 0 citations
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