Open access
Oct 2026
Group IVA Cytosolic Phospholipase A2 (cPLA2α): Pharmacological Inhibition Attenuates Kidney Inflammation and Fibrosis
Chronic kidney disease (CKD) is a significant global health burden and a leading cause of death in the United States. Chronic inflammation contributes to fibrosis and CKD progression. Here, we present evidence that a key pro-inflammatory group IVA phospholipase A2 enzyme (cPLA2α) is critical to the development of kidne...
Berit Johansen, Said Movahedinaini, L. Selvik et al.
· Biomolecules · 0 citations