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Author

O. Tsupykov

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2 papers indexed here

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Open access Oct 2026

Long-term cytotoxic skewing of CD4+CD8+ T cells after STEMI: association with immune senescence in COVID-19 patients

ST-elevation myocardial infarction (STEMI) induces long-term immune remodeling. Double-positive (DP) CD3+CD4+CD8+ T-lymphocytes represent a minor but functionally plastic subset involved in chronic inflammation and immune adaptation. However, their long-term dynamics following STEMI, particularly in patients with...

O. Parkhomenko, O. Shumakov, Vitalii Kyryk et al. · 0 citations
Review Open access Sep 2026

Functional relevance and mechanisms of necroptosis in ischemia-reperfusion injury.

Ischemia-reperfusion injury remains a major cause of mortality and disability worldwide, with limited therapeutic options. While reperfusion is essential for tissue salvage, it paradoxically triggers secondary damage, highlighting the need to better understand regulated cell death pathways. Traditionally, apoptosis was...

R. Koval, I. Lushnikova, O. Tsupykov et al. · 0 citations

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