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Author

O. N. Zauzolkov

2 papers indexed here

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Open access Oct 2026

Serial Tumor-Agnostic Plasma Profiling with a Compact NGS Panel During First-Line Therapy for Newly Diagnosed Metastatic Colorectal Cancer

Plasma circulating tumor DNA (ctDNA) profiling may complement tissue hotspot testing and reveal molecular changes during treatment of metastatic colorectal cancer (mCRC). We prospectively studied 39 patients with newly diagnosed unresectable mCRC receiving first-line therapy. Cell-free DNA was collected before treatmen...

G. Zakharova, O. Zauzolkov, A. Khristichenko et al. · 0 citations
Open access Sep 2026

Efficacy and safety profile of dMMR/MSI immunotherapy in metastatic colorectal cancer in real-world clinical practice

Introduction. Deficiency of the mismatch repair system (dMMR) and microsatellite instability (MSI) occur in only 4–5% of patients with metastatic colorectal cancer (mCRC), but this molecular subgroup is characterized by high sensitivity to immune checkpoint inhibitors. Data on the efficacy and safety of such thera...

M. Lyadova, O. N. Zauzolkov, Julia S. Mansurova et al. · 0 citations

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