Author

Okechukwu Paul-Chima Ugwu

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#explainable ai Open access Oct 2026

Pharmacometabolomic signatures as individualised biochemical response evidence: towards a precision jurisprudence framework for forensic toxicology and criminal responsibility

Precision medicine is transforming drug response from a population level assumption into an individualised biochemical event. Pharmacometabolomics, which profiles metabolic signatures associated with drug exposure and response, offers a mechanistic basis for explaining interindividual variability in therapeutic efficac...

Okechukwu Paul-Chima Ugwu, Maria Edet Umo, Richard A. Akwagiobe et al. · Frontiers in Pharmacology · 0 citations

#explainable ai Review Sep 2026

Digital twins and explainable AI across the vaccine life cycle: from mRNA manufacturing to thermostability, cold-chain logistics, and immunisation services.

The evidence indicates that DTs are progressing from static simulations to operational twins for plasmid-to-mRNA production, supporting virtual commissioning, rapid scale-up and real-time optimisation, and XAI-enabled approaches improve stability prediction, and artificial intelligence of things (AIoT) architectures st...

Ugwu Okechukwu Paul-Chima, Michael Ben Okon, F. C. Ogenyi et al. · Vaccine · 0 citations